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The patient received multiagent chemotherapy using cyclophos
2019-06-06
The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent
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The further investigation was performed
2019-06-06
The further investigation was performed by using MEM-M6/6 antibody to observe the linkage exits between CD147 and P-gp activity by intracellular Rho123 accumulation. MEM-M6/6 treatment did not alter Rho123 accumulation in drug-resistant K562/ADR cells. In contrast, the fluorescence intensity of Rho1
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Frustratingly in the past years the world has
2019-06-06
Frustratingly, in the past 40 years the world has added only two new drugs to the arsenal against tuberculosis, the second most deadly infectious disease on the planet. The statistics are infuriating: more than 9 million people developed tuberculosis in 2013, and an estimated 44% of those in countri
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The importance of social determinants on
2019-06-06
The importance of social determinants on population health is widely known. Beyond this recognition, key questions that still need to be addressed include research into how to best address social determinants through intersectoral collaboration. Pillay-van Wyk and colleagues identify this approach a
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The predicted mean time to
2019-06-06
The predicted mean time to attaining the maximal indirect impact is relevant when considering adult vaccination with PCV. Most developed countries do not recommend PCV in adults, believing that with the high coverage in the infant programme, adult disease will (eventually) decline. The US vaccine de
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In our survey the mean DEFS DMFS index was
2019-06-06
In our survey, the mean DEFS/DMFS index was higher for the 6-years-old group (17.18). During early development, younger children often have difficulty carrying out proper oral care due to their physical limitations. After 6 years of age, the exfoliation of primary teeth and the eruption of permanen
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Elderly patients especially those in excess of years
2019-06-06
Elderly patients, especially those in excess of 70 years of age, are often quite fragile; such fragility may be secondary to aging or comorbidity. In this “susceptible” patient population, the negative influence of ET-adverse events on patient adherence to a medication regimen can be elevated. This
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br As the only methods available for
2019-06-06
As the only methods available for dual protection against pregnancy and sexually transmitted infections (STIs), male and female condoms have a vital role in sexual and reproductive health. Mags Beksinska and colleagues therefore are to be commended for their randomised crossover trial in this pur
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We discussed in our report the potential
2019-06-06
We discussed in our report the potential to improve vaccine acceptance and increase demand for OPV by engaging people within communities to deliver health education. Our analysis focused on all reported sources of health education within a community—ie, not only traditional leaders but also the loca
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El otro paradigma cuyo alcance y magnitud
2019-06-06
El otro paradigma cuyo alcance y magnitud exige atención particular es la deconstrucción y todo el giro lingüístico que la precede, un enfoque en muchos sentidos inverso BMN673 la colonialidad, aunque no en todos. Sus cauces precursores en América Latina podrían partir de figuras como Irlemar Chiamp
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Se agrupan haciendo exaltaci n de la droga y del
2019-06-06
Se agrupan haciendo exaltación de la droga y del delito, tienen enemistad manifiesta con la autoridad, endiosan order Lenalidomide mitos populares, elevan a categoría de santos a los músicos muertos trágicamente, consideran mártires a los jóvenes muertos en enfrentamientos policiales o entre bandas
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Este trabajo implic otras formas de movilidad
2019-06-06
Este trabajo implicó otras formas de movilidad, fuera simbólica o material. Las armas utilizadas sugieren la capacidad armada y, paradójicamente, los rostros cubiertos ponderan el valor de la clandestinidad, PCP inhibitor la vez que rompen con la personificación individual de la lucha, que si bien l
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Curiosamente las dos obras que pueden considerarse germinale
2019-06-06
Curiosamente, las dos obras que pueden considerarse germinales del pensamiento complejo, tales como Ciencia con consciencia e Introducción al pensamiento complejo, son obras de recopilación de trabajos dispersos, aunque ramificados lógicamente. Antes que tratados sistemáticos y elaborados desde el p
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Los paradigmas de cosmopolitismo de Mito entraron
2019-06-06
Los paradigmas de cosmopolitismo de Mito entraron en diálogo con los de Jorge Luis Borges, Octavio Paz, Baldomero Sanín Cano y Alfonso Reyes; todos integraron su comité de patrocinio. Se miró atentamente la actualidad cultural de París, pero no la de la nrf, sino la que concentró Les Temps Modernes
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br Conflict of interest br Introduction Hepatosplenic T
2019-06-06
Conflict of interest Introduction Hepatosplenic T cell lymphoma (HSTCL) is a very rare type of hematologic malignancy, making up about 5% of peripheral T-cell lymphomas. It predominantly affects young male adults, with a higher incidence in patients submitted to immunosuppressive treatment for
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