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The methods of choice to assess collagen glycosylation
2020-07-30
The methods of choice to assess collagen glycosylation range from the analysis of single amino acids following alkaline hydrolysis [13] up to liquid chromatography–tandem mass spectrometry (LC–MS/MS) [12,14,15]. The low complexity of the polypeptide sequence and the intermolecular/intramolecular cov
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Cy5 carboxylic acid (non-sulfonated) br Acknowledgements The
2020-07-30
Acknowledgements The present work was funded by National Natural Science Foundation of China (No. 816712276 and No. 81771147), Natural Science Foundation of Shandong Province (ZR2016HM30), Medical and Health Development Program of Shandong Province (2016WSB33025), 2015 Science and Technology Deve
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At the time of analysis patients experienced disease progres
2020-07-29
At the time of analysis, 17 patients experienced disease progression. We managed to collect nine tissue samples and 14 plasma samples. Most common reason we were not able to obtain as many tissue samples as expected was difficulty in obtaining tissue samples due to invasiveness and patients’ poor co
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Our studies investigating a role for integrins in
2020-07-29
Our studies investigating a role for integrins in collagen induction of lysyl oxidase may also suggest a cooperative function for integrins in DDR2-mediated up-regulation of lysyl oxidase by collagen. It is interesting to note, however, that the level of 32kDa lysyl oxidase in the presence of EDTA w
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In order to further dissect the features underlying partner
2020-07-29
In order to further dissect the features underlying partner recognition by CaM, we undertook a quantitative study aimed at characterizing the complexes CaM–Can (n=0–4) involved in target interaction. Using fluorescence polarization, we analyzed the interaction between SynCaM, the product of the syn
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Fmoc-Gln(Trt)-OH br Experimental section br Results br
2020-07-29
Experimental section Results Discussion In our previous work (Rashidi et al., 2018) we isolated a novel glucarpidase whose raised Fmoc-Gln(Trt)-OH did not cross-react with the one in clinical use. In principle, therefore, it would be possible to delay the production of antibodies in a pati
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Although CPA EoS has been used previously to calculate water
2020-07-29
Although CPA-EoS has been used previously to calculate water solubility in a limited number of hydrocarbons, we proposed a general approach to evaluate water solubility in ill-defined hydrocarbon mixtures. Heavy reservoir fluids such as heavy crudes and bitumen usually remain ill-defined constituent
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The boiling point of bitumen cannot
2020-07-29
The boiling point of bitumen cannot be precisely measured, because bitumens contain extremely heavy fractions. For instance, 50 wt% of Athabasca bitumen possesses a nominal boiling point exceeding 797 K [25]. These fractions are not distillable even under vacuum pressures, because the boiling point
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Conventional configurations for alkanolamine and acid gas ar
2020-07-29
Conventional configurations for alkanolamine and FITC, Fluorescein isothiocyanate gas are not suitable to represent the chemical reaction between acid gas and alkanolamines. Nevertheless, Dowell et al. [17] have successfully represented the phase behaviour of CO2-water-MEA systems by using SAFT-VR [
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In some fish a rise in plasma progesterone P levels
2020-07-29
In some fish a rise in plasma progesterone (P4) levels and changes of mPR abundance in gonads were reported to be associated with oocyte maturation and ovulation (Kagawa et al., 1981, Kazeto et al., 2005b) and sperm mobility is also regulated by non-genomic progesterone actions in fish and mammals (
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EBI and its ligand s EBI was found in a
2020-07-28
EBI2 and its ligand(s) EBI2 was found in a screen of upregulated genes in human phenylephrine hydrochloride upon infection with EBV [1]. EBI2 is a G-protein (Gαi type) coupled receptor [2] but as long as 18 years after its discovery the nature of its ligand remained undisclosed. With the help of t
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There are numerous theories of schizophrenia etiopathology a
2020-07-28
There are numerous theories of schizophrenia etiopathology and amd3100 is often taken into consideration [25]. The dopamine D2 receptor is important since it is blocked by typical antipsychotic drugs with high affinity which is correlated with the ability to control psychotic symptoms in schizophren
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CMV replication is highly dependent on beneficial host cell
2020-07-28
CMV replication is highly dependent on beneficial host cell translation functions. As a major regulator of cap-dependent translation initiation, the activation of mTOR is essential for CMV. Activated mTOR can phosphorylate 4E-BP, eIF4G, and S6K. Further, phosphorylation of 4E-BP and eIF4G can mainta
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At the cellular level TGF has been involved in
2020-07-28
At the cellular level, TGF-β1 has been involved in the formation of invadosomes (Mandal et al., 2008, Varon et al., 2006). Invadosomes are actin-based structures involved in matrix degradation and cell invasion through metalloproteinases (MMP) activity (Linder et al., 2011). Invadosomes, constitutiv
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Concanamycin A The assessment process is even more
2020-07-28
The assessment process is even more difficult when Commercial-Off-The-Shelf (COTS) components – whose internals are partially or totally unknown – come into play. COTS are being increasingly used by the industry to reduce costs and to shorten development (and possibly deployment) time. However, sinc
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